Albendazolas

Albendazolas

Albendazolas CAS:54965-21-8

Albendazolas Chemical Properties

MF: C12H15N3O2S

MW: 265,33

EINECS: 259-414-7

Lydymosi temperatūra: 208-210 ° C

Tankis: 1,2561 (apytikslis įvertis)

Lūžio rodiklis: 1,6740 (įvertis)

Tirpumas praktiškai netirpi vandenyje, lengvai tirpsta bevandenėje skruzdžių rūgštyje, labai mažai tirpsta metileno chloride, praktiškai netirpi etanolyje (96 proc.).

Pka: 10,72 ± 0,10 (numatoma)

Tirpumas vandenyje: 0,75mg / L (209ºC)

Albendazolas CAS:54965-21-8 Specifikacija:

Albendazolas CAS:54965-21-8 Introduction:

1. Albendazolas is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal.

2. Albendazolas can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion.

Albendazolas CAS:54965-21-8 Functions

Albendazolas is an anthelmintic or anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.  

Albendazolas is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm.

1. Albendazolas is highly effective broad spectrum anthelmintic drugs, is benzimidazole deworming drugs in the broader spectrum.

2. Albendazolas is highly active against nematodes, schistosomes, tapeworms, but also significantly inhibited the development of eggs.

3. Albendazolas on parasitic nematodes in a variety of animals, schistosomes, tapeworms and cysticerci also has a significant role in repelling.

4. Albendazolas is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock.

Albendazolas CAS:54965-21-8 Application:

1. Plataus spektro antiparazitinis; Naudojamas nematodams, kaspinuočiams, trematodų kirminams ir ektoparazitams išstumti iš gyvulių.

2. Albendazolas has a broad spectrum of insect repellents, and has a strong effect on nematode, tapeworm and trematode; Its mechanism of action is to bind to microtubulin in the worm and prevent it polymerize withα-tubulin to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism.

3. Ivermektinas gerai veikia vidinius ir išorinius parazitus, ypač nariuotakojų vabzdžius ir vidinius nematodinius kirminus; Jis daugiausia naudojamas virškinimo trakto nematodiazei, plaučių kirminams ir ektoparazitams išstumti; Atvejų pašalinimo mechanizmas yra skatinti presinapsinių neuronų GABA išsiskyrimą, taip atveriant GABA tarpininkaujamus chlorido jonų kanalus; Chloro jonų srautas gali sumažinti ląstelės membranos atsparumą, sukelti nedidelį postinapsinės membranos statinio potencialo depoliarizaciją, trukdyti signalo perdavimui tarp nervų raumenų, taip pat vabzdžių kūnas atsipalaiduoti ir paralyžiuoti, o tai lemia vabzdžių kūnas.