Fenacetinas

Fenacetinas

Fenacetinas CAS:62-44-2

Fenacetinas Chemical Properties

MF: C10H13NO2

MW: 179,22

Lydymosi temperatūra: 133-136 ° C (šviečia)

Virimo temperatūra: 132 ° C / 4 mmHg

Tankis: 1.1248 (apytikslis įvertis)

Fenacetinas Specification:

Tyrimas% â ‰ ¥ 99,0

organinis chloridas% â ‰ ¤0,02

p-Phenetidineâ € 4 šviesos #

Lengvas anglies junginys - 4 # 6 € #

Nuostolis džiovinant% â ‰ ¤0,5

Lydymosi temperatūra: 134-137 ° C

Uždegimo liekanos% â ‰ ¤0.1

Fenacetinas Introduction:

Fenacetinas is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenacetinas is a pain-relieving and fever-reducing drug,

 Fenacetinas was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.

This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenacetinas has been linked to renal papillary necrosis in human beings [2, 3].

Fenacetinas Application:

Antipiretinis analgetikas, vartojamas karščiavimui, galvos skausmui, neuralgijai ir kt